Aprotinin History
Aprotinin is a protein that has been researched since the 1930s. In 1960, medical practitioners began using aprotinin during surgical procedures. However, despite being one of the most studied proteins, the physiological function of aprotinin remains unknown.
Aprotinin is derived from cattle – more specifically from bovine lungs.
Medical drug colossus, Bayer Pharmaceuticals, manufactures aprotinin as Trasylol. The US Food and Drug Administration approved aprotinin Trasylol use during surgery in 1993.
Aprotinin Medical Application
Aprotinin is injected into human beings to reduce or prevent excessive blood loss during major surgery.
When aprotinin is used – specifically in heart bypass surgery, orthopedic surgery, and liver transplantation – the need for blood transfusions is reduced because of the reduction of blood loss.
Aprotinin Effects
Aprotinin works directly against the human body’s ability to dissolve blood clots. Aprotinin also reduces normal blood flow.
Once an aprotinin injection is given, human blood reacts by coagulating faster and thus forming more clots than usual. Thus, during surgery, aprotinin stops a patient from bleeding more than usual.
Apart from reducing excessive bleeding, the effects of aprotinin prevent low blood pressure that can result in organ damage.
Aprotinin Dosage
Aprotinin is administered at the discretion of the attending physician. The aprotinin dosage likewise relies on the judgment of the doctor. In common medical practice, patients need not be informed that aprotinin or how much of it has been administered.
Aprotinin Fatality
Between the first year of aprotinin use in hospitals and surgery, 1993, and February 2006, the US Food and Drug Administration received 235 reports indicating that patients given aprotinin injections were dying.
A significant number of the patients who were given aprotinin were experiencing or dying from heart attacks, strokes and internal hemorrhages. The clotting properties of aprotinin were detrimentally creating more clots in patients.
Heart attacks, strokes, and internal hemorrhages occur when blood clots form internally, inhibiting oxygen-rich blood from reaching vital organs, such as the kidneys, heart – myocardium, pericardium and the brain. Aprotinin causes undue damage to these vital organs, and in turn, the damage can lead to death.
If you or someone you know has undergone surgery, consult with a physician immediately and confirm if aprotinin – or Trasylol, manufactured by Bayer Pharmaceuticals – was used.
The effects of aprotinin or Trasylol may be triggered only after 30 days, by which time, medical and legal recourses are limited. Consult your doctor immediately. This is an imperative. The aprotinin and Trasylol legal investigation teams at Babbitt-Johnson are at your disposal for these specialized cases.
To learn more about aprotinin and its effects, see Trasylol.
See also, Myocardium, Pericardium
It is imperative to consult a physician as soon as possible. Babbitt-Johnson attorneys, specializing in aprotinin and Trasylol cases, offer free legal consultations and advice on the best legal recourses.
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